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Bremelanotide

Bremelanotide is a cyclic heptapeptide analogue of alpha-MSH and a melanocortin receptor agonist, including at MC3R and MC4R. It is a metabolite of melanotan II, with a C-terminal acid in place of the amide, and was evaluated in clinical trials in premenopausal women with hypoactive sexual desire disorder.

Class
melanocortin receptor agonist
Type
cyclic peptide, 7 residues
Also known as
PT-141, Vyleesi, Rekynda
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Molecular formula
C50H68N14O10
Molecular weight
1025.2 g/mol
CAS number
189691-06-3
PubChem CID
9941379

Regulatory status

Approved by the FDA on 21 June 2019 (Vyleesi) for acquired, generalized hypoactive sexual desire disorder in premenopausal women.

SHLabz batch results

No SHLabz batch of Bremelanotide has a published report yet. Each batch is tested by an independent laboratory, and the report for a batch is available on request through the contact page.

Where SHLabz supplies it

PT-141 · PT-141 Nasal Spray. For laboratory research use only.

Further reading

Sources

How to cite this sheet

SHLabz (2026). Bremelanotide: compound reference sheet. SHLabz Compound Library. https://shlabz.ae/compounds/pt-141/

This sheet describes a molecule and the published research on it. It is not advice about use, and SHLabz products are not for human or veterinary use.

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