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GHK-Cu

GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, which Pickart and Thaler first reported from human plasma in 1973. It has been studied mainly in cell-culture, wound-healing and skin models, and it is used as a cosmetic ingredient (INCI name: copper tripeptide-1).

Class
copper-binding tripeptide complex
Type
copper(II) complex of a tripeptide (3 residues)
Also known as
Prezatide copper, Copper tripeptide-1, Glycyl-L-histidyl-L-lysine copper complex, Cu-GHK
Sequence
GHK (Gly-His-Lys), complexed with Cu(II)
Molecular formula
C14H23CuN6O4+
Molecular weight
402.92 g/mol
CAS number
89030-95-5
PubChem CID
71587328
First described
1973: Pickart L, Thaler MM. Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver. Nature 243:85–87.

Regulatory status

Used as a cosmetic ingredient. FDA listed injectable GHK-Cu as a compounding substance with safety concerns (immunogenicity, limited human data), and the nomination was later withdrawn.

SHLabz batch results

ProductBatchPurityAmount measuredTestedReport
GHK-Cu 50 mgSH-CU50-11202699.985%55.79 mg (GHK 47.00 mg, copper 8.79 mg)22 Oct 2026Janoshik 242758
GLOW Blend SH-GLOW70-112026Content onlyGHK-Cu 65.33 mg; BPC-157 12.03 mg; TB-500 11.04 mg22 Oct 2026Janoshik 242755
GHK-Cu 100 mgSHCU100-08202699.713%86.10 mg (GHK 75.14 mg, copper 10.96 mg)25 Aug 2026Janoshik 219641
KLOW Blend 80 mgKLOW80/2025-1010Content onlyGHK-Cu 67.81 mg; BPC-157 11.06 mg; TB-500 10.94 mg; KPV 11.08 mg03 Nov 2025Janoshik 85650

Where SHLabz supplies it

GHK-CU · GHK-CU Pen · GHK-CU Copper Peptide Serum · AHK-CU + GHK-CU Hair Spray · GLOW Blend · KLOW Blend · KLOW Blend Pen. For laboratory research use only.

Further reading

Sources

How to cite this sheet

SHLabz (2026). GHK-Cu: compound reference sheet. SHLabz Compound Library. https://shlabz.ae/compounds/ghk-cu/

This sheet describes a molecule and the published research on it. It is not advice about use, and SHLabz products are not for human or veterinary use.

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