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Delta sleep-inducing peptide

DSIP is a nonapeptide first isolated by the Schoenenberger–Monnier group from the cerebral venous blood of rabbits in which sleep had been induced; it is named for the delta-wave sleep reported in that work. It has been studied in animals and in small clinical studies, including on drug-withdrawal syndromes.

Class
neuropeptide
Type
peptide, 9 residues
Also known as
DSIP, Emideltide
Sequence
WAGGDASGE
Molecular formula
C35H48N10O15
Molecular weight
848.8 g/mol
CAS number
62568-57-4
PubChem CID
68816
First described
1977: Schoenenberger GA, Monnier M. Characterization of a delta-electroencephalogram (-sleep)-inducing peptide. PNAS 74(3):1282–1286 (isolation work dates from 1974).

Regulatory status

No approval as a medicine was found. In July 2026 an FDA advisory committee voted 6–7 against adding emideltide to the 503A bulks list.

SHLabz batch results

No SHLabz batch of Delta sleep-inducing peptide has a published report yet. Each batch is tested by an independent laboratory, and the report for a batch is available on request through the contact page.

Where SHLabz supplies it

DSIP · DSIP Nasal Spray. For laboratory research use only.

Further reading

Sources

How to cite this sheet

SHLabz (2026). Delta sleep-inducing peptide: compound reference sheet. SHLabz Compound Library. https://shlabz.ae/compounds/dsip/

This sheet describes a molecule and the published research on it. It is not advice about use, and SHLabz products are not for human or veterinary use.

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